Frequently Asked Questions

Khapregesic® FAQ

[pronounced kapprejeesic]

What are the ingredients in Khapregesic®?

There is only one active ingredient in Khapregesic® [kap-pre-jee-sic], the ancient traditional medicine plant, Khaya senegalensis.

Our one ingredient packs a punch with 3 powerful actions.

<1> It’s a potent, gentle to the stomach anti-inflammatory with pain relieving factors,

<2> It’s high in antioxidants (even higher than green tea) and

<3> has natural prebiotics for gut health.

We keep to the highest quality standards which is why our khaya is also Certified Organic and grown in Australia’s Tropical North, the most pristine agricultural land on earth.

We are also focused on purity which is why Khapregesic® [kap-pre-jee-sic] is vegan friendly and contains: No added artificial flavourings, colourings, or preservatives. It is naturally free from gluten, wheat, dairy, lactose, corn, cereals, eggs, nuts, and yeast.

Is Khapregesic® TGA approved?

Yes, Khapregesic® is TGA approved. A world first!

BioActive Natural Health are the first company in the world to have researched, grown and granted regulatory approval for the active ingredient in Khapregesic®, the ancient traditional medicine tree known as: Khaya senegalensis. This approval was granted in 2018.

The period pain product formulation known as Khapregesic® was TGA approved as a low risk Listed Medicine and entered into the Australian Register of Therapeutic Goods (ARTG) in 2019.

For a fuller explanation of the difference between a Listed Medicine and a Registered Medicine click on this TGA link:

How do I say Khapregesic® & what does it mean?

Say it like this:   


The name ‘Khapregesic’ is made up from:

  1. ‘Kha’ the traditional medicine herb Khaya senegalensis
  2. ‘pre’ for “prevents“, and
  3. ‘gesic’ from the English word ‘algesia’ meaning “sensitivity to pain” (from ancient Greek ἀλγησις)

khaya – prevents – a sensitivity to pain

What’s in Khapregesic® and where is it made?

Khapregesic® contains an ancient traditional medicine plant called Khaya senegalensis (pronounced: Ky-yar sen-ee-gal_en-sis), also known as Khaya (pronounced: Ky-yar).

Khaya is the active ingredient, and comes from sustainably-grown, Certified-Organic Australian plantations.

Khapregesic® is 100% Made in Australia with NO offshore processing.


What are the main benefits of Khapregesic®?

In addition to its pain-relieving action during menstruation, clinical case studies have revealed that Khapregesic® can ease mild anxiety, and other associated symptoms such as abdominal cramping, brain fog, bloating and diarrhoea. Most patients also reported an easing of PMT/PMS symptoms and a significant improvement in sleep patterns.

(PMT/PMS – Pre-Menstrual Tension / Pre-Menstrual Syndrome)

Are there any other benefits or uses for Khapregesic®?

Apart from easing period symptoms, it has been reported by many women to be effective in easing the pain and discomfort of endometriosis, mid-cycle ovulation, PCOS and adenomyosis

It is also being used for mild arthritis and joint pain in women with hormone fluctuations especially those during peri-menopause, menopause and post-menopause.

How fast does Khapregesic® work?

Khapregesic® has been reported in clinical tests to work within 30 minutes on average. For some women it can work as fast as 15 minutes and for others it may take a little longer.

But remember as everyone is different the effects may be quicker, delayed or not at all depending on your individual circumstances. Also ensure, if symptoms persist, talk to your health professional.

How does Khapregesic® work?

Like many medicinal plants the active ingredient in Khapregesic®, Khaya, has many properties. It is scientifically proven to be a strong anti-inflammatory and pain reliever, with high levels of anti-oxidants and prebiotics.

A long history of traditional medicine and recent clinical case studies have proven Khaya’s pain-relieving and calming qualities for pre-menstrual, menstrual and mid-cycle symptoms.

In addition, more and more people are finding relief from serious conditions such as Endometriosis, adenomyosis and PCOS.

Many people are finding it very effective post-surgery.

My first laparoscopy, I wasn’t aware of Khapregesic. This time, however, Khapregesic was my go-to for pain relief post-surgery. For fellow endo warriors, I would recommend stocking up for flare ups and post-surgery care. Khapregesic now lives in my handbag!“, Sarah

People with menstrual and menopausal mild arthritis and joint pain are also finding relief from Khapregesic® often times replacing their everyday use of ibuprofen with Khapregesic® improving their gut health and overall vitality.

Since taking Khapregesic, I noticed almost immediate relief in my fingers and have significantly reduced my need for ibuprofen. My gut health and levels of energy also seem to have improved so I’m feeling less anxious.“, Marina

I can't swallow tablets, can you crush Khapregesic®?

Here’s the customer Q&A

Q. Hi Clare, I’m looking for pain relief for my daughter with her periods. She just turned 16 and she really suffers from pain. I need to find medication that we can crush or liquid will be even better. She cannot swallow tablets 🙈

A. Hi Debbie*, you’re in luck, our daughter was averse to swallowing tablets at that age too, they do grow out of it. As a natural whole plant medication, you can crush up Khapregesic® and add it to food. It is really bitter, so something sweet like honey would be best as it is also an unrefined sugar, but just experiment to see what suits her. I’m sure it is better than the pain. Remember for best effect, take it 2-3 days before bleeding and for a duration of 7 days all up. If symptoms last longer than 7 days, just take one day off and start another 7 days.  All the best & good luck, Clare 🌸

*name changed for privacy

Can I take Khapregesic® with other medicines and supplements?

Yes, Khapregesic® [kap-pre-jee-sic] is safe to use with other medicines and supplements.

It is a TGA listed medicine for peace of mind and it is safely sold over-the-counter or online.

Always follow the directions on the bottle or the written directions from your practitioner and remember, if symptoms persist, talk to your health professional.

How should I take Khapregesic®?

Take Khapregesic® with your favourite beverage or a glass of water just like any other medication or supplement.

Remember to always follow the directions on the bottle or as directed by your practitioner and if symptoms persist talk to your health professional.

How long should I take Khapregesic®?

It is recommended to be taken 2 or 3 days before your period for 7 days all up. Most people take one in the morning and one in the evening or before bed for better sleep.

If your normal pain lasts longer than 7 days, take one day off and recommence another 7 days. 

Always follow the directions on the bottle or as prescribed by your practitioner and remember, if symptoms persist or get worse, talk to your health professional.

Does Khapregesic® have any side effects?

No, there are no known harmful side effects.

In documented traditional medicine dating back to over 100 years of use, there are no known harmful side effects. In a clinical case study of 24 patients, 1 person who was coming off a course of antibiotics and still unwell reported nausea for the first day. No other side effects were reported.

Hundreds of people now take Khapregesic® and there has not been one report of a harmful side effect.

Always follow the directions on the bottle or the written directions from your practitioner and remember, if symptoms persist, talk to your health professional.

Are there any contraindications?

Khapregesic® is not to be used if pregnant or likely to become pregnant. It is not recommended during breastfeeding. It is not recommended for children under the age of 12.

Always follow the directions on the bottle or the written directions from your practitioner and remember, if symptoms persist, talk to your health professional.

Are there any negative interactions with transexamic acid or any other drug?

Khapregesic® can be taken safely at any time and with any other food, supplement or medication.

Most people take one in the morning to setup their day and one in the evening for better sleep, for the 7 days of a menstrual cycle or up to 7 days when they have an endo flareup, PCOS, adenomyosis, mid-cycle ovulation pain or joint pain during the menstrual cycle or in menopause.

Always follow the directions on the bottle or the written directions from your practitioner and remember, if symptoms persist, talk to your health professional.

Where can I get more product information?

To get more general information click here. For Practitioner-only information click here.

What's your privacy policy?

In a nutshell, without your permission we will never share your information with an unknown third party. Who is a third party? Well the first party is us*, the second party is you, so a third party is anyone other than us and you. Rest assured your privacy rights are in good hands.

Take a look at our detailed Privacy Policy. If you need more information take a look at the rules put together by the Australian government ( and if you are in the US, the US government (

*‘us’ refers to Bioactive Natural Health Pty Ltd an Australian company incorporating our staff, contractors and suppliers.